The SOP for dry powder filling operation defines step‑by‑step controls for aseptic vial filling of sterile powders, including environmental conditions, machine setup, component transfer, in‑process weight and quality checks, and documentation. It ensures each vial receives the correct dose under…
Fumigation of a microbiology lab is a validated decontamination process that uses a gaseous disinfectant (commonly formaldehyde or hydrogen peroxide) to reduce microbial contamination on room surfaces and equipment. The SOP defines responsibilities, safety precautions, quantities, exposure time, aeration, and…
Principle of Dissolution Test Apparatus Dissolution is the analysis process in which the analyzed substance forms a solution. In this testing measurement of the content and rate of dissolving in the solution from a dosage form, such as a tablet,…
In electrochemical processes, an electrode plays a crucial role by enabling the transfer of electrons between the solution under investigation and the external circuit. This electron transfer makes it possible to detect and analyze electrochemical reactions, which have numerous applications…
In the quality control department Instrument section is an essential part because every test requires a specific instrument to perform a valid analysis. Karl Fischer titration is very essential in many analyses including finding the water content in any substance.…
According to Wikipedia the principle of Polarimeter is “The ratio, the purity, and the concentration of two enantiomers can be measured via polarimetry. Enantiomers are characterized by their property to rotate the plane of linear polarized light. “ Therefore, those…
The friability test is a prime and important physical test of tablets. It is performed while in-process and after finished product analysis. The friability usually is done to know the strength of tablets. If the tablet gets the edge broken…
When we take a tablet as medicine it looks quite good in shape and shining colors but whether it will affect good or not depends on its disintegration properties. Disintegration means releasing drug content in the body on oral consumption.…
Working standards are an integral part of any pharmaceutical laboratory. The working standard allows knowing the assay value of any tested product against the potency of the working standard. There are two types of standards in the laboratory (i) Reference…
Environment monitoring is a regular process in a pharmaceutical manufacturing company in the manufacturing area and quality control department. There are some specifications followed for environmental conditions allowed in the specified area. If the results during microbiological testings for environment…