A dry cough—medically termed a non-productive or unproductive cough—produces no mucus or phlegm. Instead, it feels like a tickle in your throat that triggers an irritating, hacking sensation. This is fundamentally different from a wet cough, where your body is…
The Indian pharmaceutical industry, currently valued at over $50 billion and targeting $130 billion by 2030, stands at a pivotal technological crossroads in the fiscal years 2025-2026. As the global leader in generic drug manufacturing and a burgeoning hub for…
By Darshan Singh | Pharma Professional (23 Years QA/QC Experience) If you are reading this, you probably have a “rattling” chest. You cough, and you can feel mucus moving, but it’s too thick to come out. That is a Productive Cough (or Wet Cough),…
The Medicines and Healthcare products Regulatory Agency (MHRA) enforces pharmaceutical manufacturing standards across the United Kingdom through a principles-based, risk-managed regulatory framework aligned with international Good Manufacturing Practice (GMP). This guide provides manufacturers, Quality Assurance professionals, and regulatory affairs teams…
MYQORZO (aficamten) represents a significant advancement in the management of obstructive hypertrophic cardiomyopathy (oHCM), a condition characterized by thickened heart muscle that obstructs blood flow out of the heart. Approved by the FDA in December 2025, it provides a targeted…
Starting a pharmaceutical manufacturing plant in India requires a carefully planned capital investment that varies significantly based on plant type, production capacity, and regulatory requirements. A basic domestic-focused tablet or capsule plant requires ₹5-15 crores minimum, while a mid-scale operation…
ALCOA stands for Attributable, Legible, Contemporaneous, Original, and Accurate—the five fundamental data integrity principles established by the FDA in the 1990s to ensure pharmaceutical data quality and regulatory compliance. These principles form the cornerstone of Good Documentation Practices (GDP) and…
Tablet compression machines, also known as tablet presses, are precision pharmaceutical manufacturing equipment designed to transform carefully formulated powders or granulated materials into tablets of uniform size, shape, weight, and hardness. These machines operate according to Pascal’s Law and the principles of hydraulic…
On December 12, 2025, the U.S. Food and Drug Administration (FDA) approved Lerochol (lerodalcibep-liga), a novel third-generation proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor developed by LIB Therapeutics, Inc. Lerochol is approved as an adjunct to diet and exercise to…
HYRNUO® (sevabertinib), a reversible tyrosine kinase inhibitor targeting HER2 (ERBB2), received FDA approval on November 19, 2025, under the accelerated approval pathway for a molecularly defined population of lung cancer patients [Approval Letter, November 19, 2025, Reference ID: 5698585]. This approval…