Lace-P Tablet is a fixed‑dose combination of Aceclofenac 100 mg and Paracetamol 325 mg used for relief of pain, inflammation and fever in adults. It is commonly prescribed in conditions like osteoarthritis, rheumatoid arthritis, musculoskeletal pain, dental pain, headache and post‑operative pain where both pain and inflammatory components are present.
Quick Product Information (Lace-P Tablet)
| Parameter | Details |
|---|---|
| Brand name | Lace-P Tablet |
| Generic name | Aceclofenac 100 mg + Paracetamol 325 mg tablets |
| Dosage form | Oral tablet |
| Therapeutic class | NSAID + Analgesic/Antipyretic |
| Indications | Pain, inflammation and fever associated with arthritis, musculoskeletal pain, dental pain, post‑operative pain, headache, body ache, sprain/strain. |
| Strength | Aceclofenac 100 mg + Paracetamol 325 mg |
| Packing | 10 × 10 Alu‑Alu (100 tablets per box) |
| MRP | ₹60.00 per 10 tablets (Lace‑P brand – update if changed) |
| Manufacturer / Marketer | Laafon Galaxy Pharmaceuticals |
| Manufactured in | India (WHO‑GMP / Schedule‑M compliant plant – if applicable) |
Composition of Lace-P Tablet
| Ingredient | Strength | Role |
|---|---|---|
| Aceclofenac | 100 mg | NSAID for anti‑inflammatory and analgesic action. |
| Paracetamol (Acetaminophen) | 325 mg | Analgesic and antipyretic for pain and fever control. |
| Excipients | q.s. | As per standard tablet formulation (non‑active ingredients). |
How Lace-P Tablet Works (Mechanism of Action)
Aceclofenac
Aceclofenac is a phenylacetic acid derivative NSAID that inhibits cyclo‑oxygenase enzymes (mainly COX‑2) and reduces synthesis of inflammatory prostaglandins. It also decreases production of pro‑inflammatory cytokines like interleukin‑1β and TNF‑α and may have a beneficial effect on cartilage glycosaminoglycan metabolism in osteoarthritis.
Paracetamol
Paracetamol (Acetaminophen) provides analgesic and antipyretic effects mainly by increasing pain threshold and acting on the hypothalamic heat‑regulating centre to reduce fever. It has weak peripheral anti‑inflammatory action compared to NSAIDs but complements Aceclofenac for pain and fever relief.
Synergistic action of Aceclofenac + Paracetamol
The combination of Aceclofenac and Paracetamol targets both peripheral inflammatory pathways and central pain/fever pathways. This dual mechanism can provide better pain relief at relatively lower individual doses compared to using higher‑dose monotherapy, which may help improve tolerability in short‑term use.
Indications and Uses of Aceclofenac and Paracetamol Tablets
Lace-P Tablet (Aceclofenac 100 mg + Paracetamol 325 mg) may be prescribed by a registered medical practitioner for:
- Osteoarthritis, rheumatoid arthritis and other inflammatory joint disorders.
- Low back pain, cervical spondylosis and other musculoskeletal pains.
- Dental pain (post‑extraction, root canal), post‑operative pain and trauma‑related pain.
- Pain with fever such as in viral illnesses or inflammatory conditions, when an NSAID is considered appropriate.
Note: This medicine should always be used on the advice of a healthcare professional. Self‑medication for more than a few days is not recommended.
Dosage and Administration
- Typical adult dosage: 1 tablet of Aceclofenac 100 mg + Paracetamol 325 mg taken orally twice daily (every 12 hours) or as directed by the physician.
- Maximum dose: Do not exceed the total daily dose prescribed by your doctor (commonly not more than 2 tablets per day for prolonged use; higher short‑term dosing, if any, should be strictly supervised).
- Administration:
- Take the tablet after food with a full glass of water to reduce gastric irritation.
- Do not crush or chew unless advised; swallow whole.
- Duration of use:
- Use the lowest effective dose for the shortest possible duration needed to control symptoms, especially in patients with cardiovascular, renal, hepatic or GI risk.
Children, pregnant women, breastfeeding mothers and patients with significant comorbidities must use this medicine only under strict medical supervision or may require alternative therapy.
Side Effects of Lace-P Tablet
Like all NSAID‑containing combinations, Aceclofenac + Paracetamol tablets may cause side effects in some patients.
Common side effects (usually mild and reversible):
- Nausea, vomiting, abdominal pain or discomfort.
- Diarrhoea or constipation.
- Heartburn, acidity, indigestion.
- Loss of appetite, mild headache or dizziness.
Serious but less common side effects (seek urgent medical attention):
- Signs of gastrointestinal bleeding (black/tarry stools, blood in vomit, severe stomach pain).
- Severe allergic reaction (rash, itching, swelling of face/lips, difficulty breathing).
- Yellowing of eyes or skin, dark urine, unusual tiredness – possible liver injury.
- Reduced urine output, swelling of legs/ankles – possible kidney impairment.
Stop the medicine and contact your doctor immediately if any serious or unusual symptoms appear.
Contraindications and Warnings
Do not use Aceclofenac + Paracetamol tablets without medical advice if you have any of the following:
- Known allergy to Aceclofenac, Paracetamol, other NSAIDs (e.g., Diclofenac, Ibuprofen) or excipients.
- Active or history of peptic ulcer, GI bleeding or perforation.
- Severe liver disease, severe kidney impairment or severe heart failure.
- History of aspirin/NSAID‑induced asthma, bronchospasm or severe allergic reactions.
- Third trimester of pregnancy (NSAIDs are generally avoided).
Use with caution and only under supervision in:
- Elderly patients.
- Patients with controlled hypertension, mild‑to‑moderate renal or hepatic impairment.
- Patients taking other hepatotoxic drugs (e.g., high‑dose anti‑TB drugs, some antiepileptics) or chronic alcohol users.
Avoid alcohol during treatment due to increased risk of liver toxicity and GI side effects.
Drug Interactions
Aceclofenac + Paracetamol may interact with the following medicines:
- Other NSAIDs, high‑dose aspirin or corticosteroids – may increase GI side effects.
- Anticoagulants (e.g., warfarin), antiplatelet agents – higher bleeding risk.
- Certain antihypertensives and diuretics – possible reduction in effect and increased renal risk.
- Methotrexate, lithium, some antibiotics (e.g., quinolones) – altered levels/toxicity risk.
- Enzyme inducers like rifampicin, some antiepileptics – may impact Paracetamol metabolism and liver risk.
Always inform your doctor about all medicines, supplements and herbal products you are taking.
Lace-P Tablet Price, Pack Size & Availability in India
| Detail | Information |
|---|---|
| Brand | Lace-P Tablet |
| Generic | Aceclofenac 100 mg + Paracetamol 325 mg tablets |
| Pack size | 10 × 10 Alu‑Alu |
| MRP (India) | ₹60.00 per strip of 10 tablets (update as per current label) |
| GST / Schedule | [To be filled as per product label] |
| Availability | Prescription‑only medicine, for sale by Retailers and Wholesalers only in India. |
For updated pricing and stock availability, please contact our sales team or your local distributor.
Lace-P vs Other Aceclofenac + Paracetamol Brands in India
This table is for information only; trademarks belong to respective companies. Prices are indicative and may change.
| Brand (India) | Company | Composition | Approx. MRP (₹) per strip | Notes |
|---|---|---|---|---|
| Lace-P | Laafon Galaxy Pharmaceuticals | Aceclofenac 100 mg + Paracetamol 325 mg | 60 (10 tablets) – update if needed | Alu‑Alu, PCD/third‑party available. |
| Zerodol‑P | Ipca Laboratories | Aceclofenac 100 mg + Paracetamol 325 mg | 75.94 | Widely prescribed brand. |
| Aldigesic‑P | Alkem | Aceclofenac 100 mg + Paracetamol 325 mg | 119.5(15’s strip) | Established brand in pain segment. |
| Dolokind Plus | Mankind | Aceclofenac 100 mg + Paracetamol 500 mg | 85.35 (15’s strip) | Higher Paracetamol strength. |
| Movexx‑P | Cipla | Aceclofenac 100 mg + Paracetamol 500 mg | 139.69 | Popular in orthopaedic OPD. |
Manufacturing & Third‑Party / PCD Opportunity
Lace-P Tablet is manufactured in a WHO‑GMP / Schedule‑M compliant facility in India with stringent in‑process controls, validated processes and stability‑tested formulations (details to be inserted as per your plant and approvals).
Key manufacturing and business highlights:
- Standard batch sizes suitable for both domestic and export markets.
- Alu‑Alu blister packing for better moisture protection and shelf‑life.
- Support with product artwork, promotional inputs and regulatory documentation (COA, MOA, stability data where applicable).
- PCD franchise and third‑party manufacturing available for Aceclofenac 100 mg + Paracetamol 325 mg tablets and related pain‑management ranges.
Enquire now for Lace-P Tablet (Aceclofenac 100 mg + Paracetamol 325 mg) PCD franchise / third‑party manufacturing – Contact Us OR WhatsApp Us.
How to Use Pain Medicines Safely
- Do not use Aceclofenac + Paracetamol tablets for long periods without medical supervision.
- Avoid combining with other Paracetamol‑containing products to prevent overdose.
- Do not consume alcohol while on this medicine.
- Inform your doctor about any history of ulcers, liver disease, kidney disease, heart disease, asthma or bleeding tendencies.
- If pain or fever persists beyond the duration advised, do not increase the dose on your own; seek medical review.
FAQs on Aceclofenac 100 mg + Paracetamol 325 mg Tablets
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What is Lace-P Tablet used for?
Lace-P Tablet is used to relieve pain, inflammation and fever in conditions like osteoarthritis, rheumatoid arthritis, musculoskeletal pain, dental pain, headache and post‑operative pain, as prescribed by a doctor.
-
Can I take Aceclofenac + Paracetamol for a long time?
Long‑term use of NSAID + Paracetamol combinations may increase the risk of stomach ulcers, kidney problems and liver injury, so they should be used for the shortest duration under medical supervision.
-
Is Lace-P Tablet safe in pregnancy or breastfeeding?
NSAIDs like Aceclofenac are generally avoided, especially in the third trimester; Paracetamol alone is usually preferred if required. Pregnant or breastfeeding women should consult their doctor before using this medicine.
-
Can I take Lace-P Tablet with other painkillers?
Do not combine Lace-P Tablet with other NSAIDs or high‑dose Paracetamol unless your doctor specifically advises it, due to higher risk of side effects.
Related Products in Pain Management
- Lace‑SP Tablet – Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg tablets (enhanced anti‑inflammatory action).
- Laadic‑MR Tablet – Diclofenac Sodium 50 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg muscle relaxant tablets.
- Laadic‑P Tablet – Diclofenac Potassium 50 mg + Paracetamol 325 mg tablets for acute pain.
References
- CIMS / MIMS drug monograph – Aceclofenac + Paracetamol.
- Apollo Pharmacy – Aceclofenac + Paracetamol uses and side effects.[https://www.apollopharmacy.in/salt/Aceclofenac+paracetamol]
- Yashoda Hospitals – Aceclofenac uses, precautions and adverse effects.[https://www.yashodahospitals.com/medicine-faqs/aceclofenac/]
- WHO‑GMP/Schedule‑M guidelines and internal quality documentation (for manufacturing claims).
- Additional peer‑reviewed clinical and pharmacology papers as already listed by you.
Reviewed by;
Dr. Yogesh Chaudhary (B. Pharma)
Senior Pharmacist at S.N. Medical College, Agra-(UP)
Disclaimer:
Disclaimer: All the information and articles available on this site are for educational purposes only. The information given here should not be used for the diagnosis or treatment of any health problem or disease without expert advice. The advice of a qualified medical practitioner should always be sought for medical examination and treatment.
