Montek-LC is a widely prescribed medication in India for managing allergies, asthma, and respiratory symptoms. Combining Montelukast (10mg) and Levocetirizine (5mg), this dual-action tablet tackles allergic reactions and inflammation effectively. In this comprehensive guide, we’ll explore its uses, mechanism, safety, substitutes, and why it’s a go-to choice for doctors.
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What is Montek-LC Tablet?
Montek-LC is a prescription-only medication covered under Schedule H Drugs, manufactured by Sun Pharmaceuticals, India’s largest generic drug producer. It’s prescribed for treating:
- Allergic rhinitis (sneezing, runny nose, itchy eyes)
- Chronic hives
- Asthma (maintenance therapy)
- Exercise-induced bronchoconstriction
- Cold-related congestion and cough
Sun Pharma’s strict quality control ensures Montek-LC meets global standards, contributing to its popularity among physicians and patients.
Montek LC Composition & Mechanism of Action
Each film-coated tablet contains: Montelukast Sodium IP Eq. to Montelukast 10mg, Levocetirizine Dihydrochloride IP 5 mg. Excipients as quantity sufficient.
1. Montelukast Sodium (10mg)
- Class: Leukotriene receptor antagonist (LTRA).
- Role: Blocks leukotrienes, inflammatory molecules that trigger asthma and allergies.
- FDA Approved Uses:
- Asthma prevention (Global Initiative for Asthma Guidelines).
- Seasonal allergies (FDA-approved).
2. Levocetirizine Dihydrochloride (5mg)
- Class: Third-generation antihistamine.
- Role: Inhibits histamine (H1 receptors), reducing itching, sneezing, and rashes.
- Benefits: Minimal sedation compared to older antihistamines like cetirizine.
Synergy: Together, they target both leukotrienes and histamine, offering dual relief from allergic and inflammatory responses.
Montek-LC Tablet Uses: Evidence-Based Benefits
1. Allergic Rhinitis & Cold Symptoms
- Relieves sneezing, nasal congestion, and watery eyes within 1-2 hours.
- Reduces airway inflammation, easing breathing during colds.
2. Chronic Cough & Asthma
- Montelukast’s anti-inflammatory action helps manage cough-variant asthma.
- Often paired with inhalers for long-term asthma control.
3. Skin Allergies & Hives
- Levocetirizine reduces itching and rashes in chronic urticaria.
4. Exercise-Induced Breathing Issues
- Prevents bronchospasm triggered by physical activity.
Side Effects: What to Watch For
While generally safe, Montek-LC may cause:
- Common: Headache (15% of users), drowsiness, dry mouth.
- Rare: Mood changes (agitation, depression), liver enzyme elevation.
FDA Warning:
Montelukast has a black box warning for neuropsychiatric side effects (e.g., suicidal thoughts). Use under strict medical supervision.
Drug Interactions & Precautions
Avoid With:
- CNS Depressants: Alcohol, benzodiazepines (increased drowsiness).
- Enzyme Inducers: Rifampicin, phenytoin (reduce Montelukast’s efficacy).
Who Should Avoid It?
- Liver/Kidney Disease: Dose adjustments are required.
- Pregnancy: Safe in most cases, but consult a doctor.
Montek-LC for Cough: How Effective Is It?
Montek-LC is not a primary cough treatment but helps when cough stems from:
- Postnasal drip (allergy-related).
- Asthma-induced coughing.
- Cold-related airway inflammation.
Clinical Support: A 2020 study found Montelukast reduced cough frequency by 40% in allergy patients.
Substitutes & Cost Comparison
| Brand Name | Price (₹) | Manufacturer |
|---|---|---|
| Montek-LC | 373 | Sun Pharma |
| Zinte-M | 99.00 | Laafon Galaxy Pharmaceuticals |
| Levocet-M | 108.75 | Hetero Labs |
| Montemac-L | 163.00 | Macleods Pharmaceuticals |
Tip: Generics contain the same active ingredients or biosimilars but may differ in binders and dissolution properties of the product. Consult your doctor before switching.
Manufacturers of Montek LC:-
Montek LC is manufactured and marketed by Sun Pharmaceuticals Ltd. It is the largest pharmaceutical company in India. Sun Pharmaceutical number 1 manufacturer in the generic medicine segment in India.
Packing of Montek LC
Montek LC tablet is available in alu alu 10*10 packing.
Price of Montek LC tablet?
The price of the Montek LC tablet is Rs. 373 per strip of 10 tablets.
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FAQs
Can I take Montek-LC for a dry cough?
Yes, if the cough is allergy or asthma-related. Avoid self-medication. But do not try self-medication always take the advice of a health professional.
How long does it take to work?
Symptom relief starts in 1-2 hours; full effect may take 1-2 weeks. The results may differ from patient to patient depending on the physical status, age, and severity of the disease.
Is drowsiness common?
Levocetirizine causes mild drowsiness in 10% of users.
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Conclusion:
Montek-LC’s dual-action formula makes it a versatile option for allergies, asthma, and cough. While priced higher than generics, Sun Pharma’s quality assurance justifies the cost. Always use it under a doctor’s guidance to mitigate risks like mood changes or liver issues.
References:
- Sun Pharma Quality & Manufacturing:[ Source: Sun Pharmaceutical Industries Ltd. Q3 Report 2024-2025.(https://www.reuters.com/business/healthcare-pharmaceuticals/indias-top-drugmaker-sun-pharmas-q3-profit-beats-estimates-strong-local-sales-2025-01-31/)]
- Bronchodilators & Mast Cell Stabilizers(Montelukast)/Drug Today(Year book 2017) Page 346.
- Montelukast Mechanism & Leukotriene Inhibition [Source: National Institutes of Health (NIH). “Montelukast: A Comprehensive Review.”]
- GINA Guidelines for Asthma [Source: Global Initiative for Asthma (GINA). “2023 GINA Report.”]
- Montelukast-Pubchem
- FDA Approval of Montelukast [Source: U.S. Food and Drug Administration (FDA). “Singulair (Montelukast) Label.”]
- Levocetirizine Safety & Minimal Sedation [Source: Church, M.K., & Maurer, M. (2017). British Journal of Clinical Pharmacology.]
