FTOX-AM Syrup: Uses, Dosage, and Effectiveness:
Ftox-AM syrup i.e. Ambroxol Terbutaline Guaiphenesin and Menthol Syrup. Ftox-Am syrup is a therapeutic solution for respiratory conditions such as productive cough, bronchitis, and related disorders. Ingredients present in the syrup are very effective when they are used as a combination in a liquid oral formulation.
Ftox-AM syrup provides fast relief in productive cough because of dual bronchodilation, and mucolytic benefits of the medication.
Table of Contents
Role of Each Ingredient in Ftox-AM syrup:
Ftox-AM consists of four powerful ingredients; Ambroxol Hcl, Terbutaline Sulphate, Guaiphenesin, and Menthol. The role of each ingredient is significant and unique in the formulation.
Ambroxol Hydrochloride:
Ambroxol Hydrochloride is a mucolytic class drug that works by breaking down mucus into smaller molecules. It helps to expel the mucus out easily. Several reference studies have shown its efficacy in chronic bronchitis and COPD.
Ambroxol stimulates the production of surfactant that is present in the airways and keeps it moist. It helps to produce less mucus when the airways remain moist.
The dosage of ambroxol varies according to the age, symptoms, and dosage form it is intended to use in patients. The usual dose of ambroxol in tablet is 30mg and in liquid oral, it is 15mg/ 5ml to 30mg/ 5 ml with single or multiple co-ingredients.
Terbutaline: Managing Bronchial Spasms and Wheezing
Terbutaline is a bronchodilator in nature. It works by relaxing the muscles in the airways widening the airways and making it easier to breathe.
Terbutaline sulfate is a beta-2 adrenergic receptor agonist, therefore, it can bind and activate beta-2 receptors. Beta-2 receptors are found on the surface of cells in the body and in the airways. Due to its significant effect on Beta-2 receptors, Terbutaline is able to provide relaxation to muscles in the airways help to them breathe easier.
Terbutaline inhibits the release of inflammatory mediators that can help to reduce the inflammation in the airways.
Terbutaline sulphate increases the size of airways which helps to breathe easily.
Guaiphenesin: Enhancing Expectorant Action
Guaifenesin is an expectorant in nature. It helps to loosen and remove the mucus from the airways. It increases the volume of mucus by diluting its viscosity in the respiratory tract secretions. This process makes coughing out the mucus easier.
Guaiphenesin is available in several types of cough syrup, as a single ingredient or with other Brochidilator, mucolytics, and suppressants like Terbutaline, Ambroxol, and Bromhexine. It is also available in tablet or capsule forms. It is usually taken by mouth as an oral medicine. However, it can also be given by injection.
The dosage of Guaiphenesin depends on the age, symptoms, and severity of cough. The accurate dose is advised by the doctor for a particular patient.
Menthol: Soothing Throat Irritation and Congestion
Menthol is an organic medicine that is used in plant form as well as processed compound forms. It is used in medicine and the food industry for cooling and soothing effects on the throat. In cough syrups, it produces a sensation of coolness and relieves minor throat irritation. It is used in cough syrups, cough drops, and lozenges.
The dosage of Menthol is different in different dosage forms, It is 0.5 mg to 2.5 mg per 5 ml in oral syrups and cough syrups.
Uses of Ambroxol Terbutaline Guaiphenesin and Menthol syrup
It is a very popular syrup among people suffering from a productive cough, irritating cough, or cough with chest sounds. Since it contains Guaiphenesin, it loosens the mucus and helps to take breath easily. It provides a way of breathing by unblocking the vessels of the nose and lungs. It is used in the following conditions
- Asthma
- Bronchitis
- cough with mucus
- Chronic obstructive pulmonary disease (COPD)
- Inflammation of bronchial tubes
- Emphysema
- Upper respiratory tract infections.
Dosage and Administration:
Potential Side Effects and Warnings of Ftox-AM Syrup
Ftox-AM syrup is a combination of Ambroxol, Terbutaline sulfate, Guaiphenesin, and Menthol. It is used to relieve cough and congestion. Since it is a potent combination, it may have some side effects that are listed here:
- Nausea
- Diarrhea
- Vomiting
- Stomach discomfort
- Sweating and muscle cramps
- Dizziness
- Headache
- Rash
- Tremor (shakiness)
- Palpitations (uneven heartbeat)
- Increased heart rate.
Safety and Precautions:
Ambroxol, Terbutaline Sulfate, Guaiphenesin, and Menthol syrup are fixed-dose combination medicines (FDC) that are not found thumb rule safe for all. Since it has four different category molecules, there are limited clinical trial safety data for the combination. You should not use this combination OR consult your doctor if you have the following symptoms:
- Heart disease
- Liver ailments
- Kidney diseases
- Stomach ulcers
- High blood pressure
- Thyroid disorders
- Inflammation of air passages
- Lung disorders
- Seizures
- Uncontrolled diabetes
- Hypokalemia (low potassium levels in the blood)
- Difficulty in breathing
- If you are a Pregnant woman
Short description
Brand Name: FTOX-AM
Dosage Form: Liquid Oral/ Syrup
Composition: Ambroxol Hydrochloride 15 mg, Terbutaline Sulphate 1.25 mg, Menthol 2.5 mg & Guaiphenesin 50mg./ 5 ml
Packing: 100 ml pet bottle, 100 bottles in a carton box.
MRP: Rs. 92.00
Also Available;
FTOX-DX : (Dextromethorphan Hbr 10mg.+CPM 2mg.+Phenylephrine HCL 5mg. sorbitol (70%)
Dosycal Plus Softgel: (Calcium, calcitriol and zinc softgel )
Protilaa Powder: Protein Powder
LOBULAR-GM: (Clobetasol Propionate 0.5%, Neomycin Sulphate 0.5 %, Miconazole Nitrate 2% Cream.
Faster gel: Diclofenac, Linseed Oil, Salicylic acid, and Menthol gel
Tinto-MH Cream: (Mometasone, Tretinoin, and Hydroquinone Cream)
COZICOF-LS : Ambroxol Hcl 15 mg+Levasalbutamol 1mg.+Guaiphenesin 50mg/5 ml
Fonvital Plus: Ginseng with Multivitamins, Minerals & Antioxidants capsules
Conclusion:
In this article, we tried to provide a comprehensive overview of FTOX-AM Syrup, focusing on its composition, mechanism of action, clinical applications, and competitive positioning. Key ingredients—Ambroxol, Terbutaline, Guaiphenesin, and Menthol—work synergistically to relieve productive cough by thinning mucus, relaxing airways, and soothing throat irritation. Detailed insights from clinical studies substantiate the effectiveness of these components. A comparative analysis highlights 10 similar products, emphasizing FTOX-AM’s unique benefits.
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Frequently Asked Questions:
What is Ambroxol guaiphenesin terbutaline menthol syrup used for?
Ambroxol, Guaiphenesin, Terbutaline, and Menthol syrup are commonly used to treat respiratory conditions that include cough, congestion, difficulty breathing, and greasy phlegm formation.
References:
- Bronchodilators [NHS(dot)com]
- Ambroxol [Pediatriconcall(.com)/Child Healthcare/Drug Index]
- How does terbutaline work? [MedicineHow]
- Guaifenesin by Melisa Puckey, B. Pharma [Drug(.com)]
- Menthol -About Menthol [Lybrate(.com)]
- Malerba M, Ragnoli B. Ambroxol in the 21st century: pharmacological and clinical update. Expert Opin Drug Metab Toxicol. 2008 Aug;4(8):1119-29. doi: 10.1517/17425255.4.8.1119. PMID: 18680446.
Disclaimer:
Disclaimer: All the information and articles available on this site are for educational purposes only. The information given here should not be used for the diagnosis or treatment of any health problem or disease without expert advice. The advice of a qualified medical practitioner should always be sought for medical examination and treatment.
Reviewed by;
Dr. Yogesh Chaudhary, B. Pharm
Senior Pharmacist at S.N. Medical College, Agra-(UP)
