Living with chronic pain or muscle spasms can feel like carrying a heavy weight every day. Whether it’s osteoarthritis, back pain, or post-injury discomfort, finding effective relief is crucial. Include Aceclofenac, Paracetamol, and Chlorzoxazone tablets i.e. Lace-MR Tablet: a triple-action combo that’s become a go-to solution for millions in India. But what makes this combination so powerful? Let’s break it down, explore the science, and list the top brands dominating the market in India.

Know about the Ingredients of the Lace-MR Tablet in detail

1. Aceclofenac (100mg):
   A non-steroidal anti-inflammatory drug (NSAID) that blocks enzymes (COX-1 and COX-2) responsible for pain and swelling. Ideal for arthritis and musculoskeletal disorders.
2. Paracetamol (325mg):
   A trusted analgesic and antipyretic that reduces fever and mild-to-moderate pain by targeting brain receptors. Safer for the stomach compared to other NSAIDs.
3. Chlorzoxazone (250mg):
   A muscle relaxant that calms spinal reflexes, easing stiffness and spasms caused by injuries or strain

Power of Combination of Aceclofenac Paracetamol and Chlorzoxazone?

Together, these three (Aceclofenac, Paracetamol, and Chlorzoxazone) tackle pain from all sides: inflammation (Aceclofenac), fever and pain (Paracetamol), and muscle tension (Chlorzoxazone). Several studies show combinations like this improve compliance by reducing pill burden while enhancing efficacy.

It is always good to take one tablet instead of three different, emotionally it is easy to accept that only one tablet is curing my health for a patient.

Uses and Indication of Aceclofenac Paracetamol & Chlorzoxazone Tablets?

Doctors prescribe this fixed-dose combination for:

• Osteoarthritis and rheumatoid arthritis
• Lower back pain or muscle spasms
• Post-surgical or dental pain
• Sports injuries or tendonitis.

Clinical Studies:

According to a study conducted in India over 100 patients with lower back pain: “Over a 7‑day period—with assessments on day 1 (baseline), day 3, and day 7—the study measured pain intensity using a visual analog scale and evaluated muscle spasm via hand-to-floor distance and Lasegue’s maneuver. Although both groups showed statistically significant improvements, Group A (thiocolchicoside + aceclofenac) had a slightly better clinical improvement and a more favorable safety profile (notably, Group B experienced more sedation and gastrointestinal side effects).

This study demonstrates that while the combination of chlorzoxazone, aceclofenac, and paracetamol is effective in relieving pain and muscle spasms, its adverse effect profile may be a consideration when compared to alternative combinations like Thiocolchicoside + Aceclofenac.”

Safety First: Side Effects & Precautions

Common Side Effects:

• Nausea, heartburn, or dizziness (due to Aceclofenac).
• Rare liver issues (from excessive Paracetamol However 325mg would not cause harm normally).

Who Should Not Use Aceclofenac, Paracetamol & Chlorzoxazone Tablets?

• Pregnant/breastfeeding women
• Patients with ulcers, liver disease, or asthma
• Those on blood thinners or diuretics.

Note: Take these tablets after meals to reduce stomach irritation, and avoid consuming alcohol on that day because it increases liver damage risk.

The Indian Market Boom: Why This Combo is a Hit

India’s pharmaceutical industry is thriving, with the paracetamol market alone projected to hit $14.25 billion by 2030. The Aceclofenac combo’s popularity stems from:

1. Cost-Effectiveness: Brands like Lofen MR cost as little as ₹30 per strip.
2. Versatility: Treats multiple symptoms at once.
3. Quality Assurance: Most brands follow WHO-GMP guidelines.

SHORT DESCRIPTION

Brand Name: Lace-MR

Dosage Form: Tablets

Composition:  Aceclofenac 100mg, Paracetamol 325mg, and Chlorzoxazone 250mg Tablets

Packing: 10*10 Alu Alu

MRP: Rs.124.00

SELF-LIFE: 2 YEARS

Substitutes of Lace-MR Tablet in India

FAQs:

Conclusion

Aceclofenac, Paracetamol, and Chlorzoxazone tablets offer a holistic approach to pain management, blending anti-inflammatory, analgesic, and muscle-relaxing powers. With top brands like WAYLAC-MR and ACYTON-MR leading the charge in India’s pharma market, relief is just a pill away—but always under medical guidance. Stay informed, stay safe, and take that first step toward a pain-free life!

Got more questions? Drop them below—we’re here to help!

References:

1. Efficacy and Safety of Combination of NSAIDs and Muscle Relaxants in the Management of Acute Low Back Pain [https://pmc.ncbi.nlm.nih.gov/articles/PMC6513919/]
2. Aceclofenac-PubChem-National Library of Medicines [https://pubchem.ncbi.nlm.nih.gov/compound/Aceclofenac]
3. Waylone Healthcare (2024). Top 10 Aceclofenac Brands in India.
4. Truemeds (2024). Aceclofenac + Paracetamol + Chlorzoxazone FAQs.
5. Index Repository (2024). Clinical Uses & Drug Interactions.
6. Sanjeev Kumar et al., “To compare the efficacy and safety of the fixed-dose combination of thiocolchicoside and aceclofenac versus chlorzoxazone, aceclofenac and paracetamol in patients with acute lower backache associated with muscle spasm,” Int J Appl Basic Med Res, 2014;4(2):101–105(https://pmc.ncbi.nlm.nih.gov/articles/PMC4137632/)